This depends on the type of data modified. Real-time Parameters (Memory Mods): Features such as 'Infinite Health' or 'One-Hit Kill' will expire immediately once you close the trainer or restart the game. Permanent Data (Save File Mods): Such as 'Adding Gold' or 'Skill Points'. Once these values are modified and saved via 'Auto-save' or a manual save in-game, the changes will remain permanently in your local save file even after GameBuff is closed.
